Endocrine Abstracts

Introduction: The information on prognosis morbidity chronic autoimmune thyroiditis and relationship with coronavirus disease 2019 (COVID-19) is lacking but endocrine involvement has been increasingly reported. The symptoms of thyroid’s dysfunction can be due to relationship after SARS-CoV-2 infection. In addition, the patients with COVID-19 leading to an increased risk of post COVID-19 complications of chronic autoimmune thyroiditis. As such, post COVID-19 complications ...

A major cause of morbidity is post COVID-19 complications. The symptoms of carbohydrate dysfunction can be due to has relationship with coronavirus disease. In patients with chronic disorders after SARS-CoV-2 infection, aggravation of pre-existing symptoms has also been noticed. Diabetes insipidus (DI) may be at risk of dysnatraemia when developing respiratory complications of COVID-19. Particularly, the combination of two or more concurrent disorder is a major problem in pati...

IntroductionRecently, there has been an increasing number of reports about subacute thyroiditis (SAT) developing after COVID-19. SAT and transient gestational thyrotoxicosis constitute the majority of emerging thyrotoxicosis during pregnancy.Case reportA 27-year-old, 34-week pregnant women complained of pain in a very small area on the anterior side of her neck and fatigue. Thyroid function tests performed fo...

Introduction: Decrease in thyroid hormones (TH) levels is associated with reduced blood flow to kidneys and decreased glomerular filtration rate (GFR) along with alteration of tubular reabsorption.Deiodinase type 1 is an enzyme that is active in liver and kidneys and plays an important role in TH metabolism.The aim of the research was to study the dependence of markers of renal function on C/T polymorphism in the DIO 1 gene in pati...

Introduction: Chronic kidney disease (CKD) is one of the leading causes ofdisability and mortality in patients with diabetes mellitus. Existence of specific phenotypes of diabetic kidney disease (DKD) is established nowadays. The prevalence of the classic albuminuric phenotype has decreased by 24% over the past decade (NHANES).The purpose of our work was to investigate the phenotypic features of DKD depending on the type of diabetes.<p class="abstext...

Introduction: Diabetes mellitus is known as a factor of cognitive impairment. The risk of dementia in patients with type 2 diabetes mellitus (T2DM) increases almost twice. The results of epidemiological, visualization and autopsy studies showed the presence of both cerebrovascular and neurodegenerative mechanisms of brain lesions. Cell death of key substrates – neurons and endothelial cells lays in the basis of the formation of cerebral disorders. Granzyme B (GrB) is a s...

Introduction: In order to improve the early diagnostics of cholelithiasis in patients with chronic acalculous cholecystitis combined with diabetes mellitus type 2 (DM), individual parameters are usually not sufficient. Therefore, we decided to establish and analyze the correlation between the serum and biochemical parameters of bile to evaluate biochemical connections in a system of lipid homeostasis by comorbid pathology. The aim of our study was to determine the peculiaritie...

Introduction: Thyroid hormones affect sex hormone metabolism and reproductive function in women. Infertility in women with autoimmune thyroiditis is more difficult to treat than in women with normal thyroid function. On the other hand, immune factors are dependent on exogenous and endogenous factors, interrelated with hormones and are important regulators of fertility, autoimmune reactionsand can lead to infertility and increase the risk of pregnancy complications and miscarri...

Introduction: The prevalence of manifest hypothyroidism by various data is 0.2–2%, sub-clinical – up to 3% in men and up to 10% in women, and in people over 70 years old – 13–14%. The presence of concomitant gastrointestinal diseases significantly limits the possibility of hypothyroidism compensation; these patients need higher doses of levothyroxine. According to a number of researchers, hypothyroidism is often accompanied by small intestinal bacterial...

Background: Vitamin D deficiency is a major public health problem in Ukraine. The aim of this cross-sectional study was to study the status of Vitamin D and parathyroid hormone (PTH) level in women of reproductive age in Carpathian region.Materials and methods: A cross-sectional study was carried on a total of 416 nonpregnant and nonlactating women in the reproductive age group of 19–45 years during summer 2018. Demographic, socioeconomic class, an...